CDK5RAP2
Protein with roles in formation and stability of microtubules / From Wikipedia, the free encyclopedia
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CDK5 regulatory subunit-associated protein 2 is a protein that in humans is encoded by the CDK5RAP2 gene. It has necessary roles in the formation and stability of microtubules from the centrosome[5] and has been found to be linked to human brain size variation in males.[6] Multiple transcript variants exist for this gene, but the full-length nature of only two has been determined.[7][8]
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CDK5RAP2 is homologous to the Drosophila protein centrosomin (cnn)[9] and paralogous to myomegalin, which in mammals contains an Olduvai domain, a domain implicated in human brain size evolution.[10][11]