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CD200R1
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Cell surface transmembrane glycoprotein CD200 receptor 1 is a protein that in humans is encoded by the CD200R1 gene.[5][6][7] CD200R1 is expressed on the surface of myeloid cells[8] and CD4+ T cells.[9] It interacts with CD200 transmembrane glycoprotein that can be expressed on variety of cells including neurons,[10] epithelial cells,[11] endothelial cells,[12] fibroblasts,[13] and lymphoid cells.[14]
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CD200R1 activation regulates the expression of pro-inflammatory molecules such as tumor necrosis factor (TNF-alpha),[15] interferons, and inducible nitric oxide synthase (iNOS).[16]