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Brompheniramine
Chemical compound / From Wikipedia, the free encyclopedia
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Brompheniramine, sold under the brand name Dimetapp among others, is a first-generation antihistamine drug of the propylamine (alkylamine) class.[2] It is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing. Like the other first-generation drugs of its class, it is considered a sedating antihistamine.[2]
Quick Facts Clinical data, Trade names ...
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Clinical data | |
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Trade names | Bromfed, Dimetapp, Bromfenex, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682545 |
Routes of administration | By mouth |
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Pharmacokinetic data | |
Metabolism | Liver |
Elimination half-life | 24.9 ± 9.3 hours[1] |
Excretion | Kidney |
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ECHA InfoCard | 100.001.507 ![]() |
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Formula | C16H19BrN2 |
Molar mass | 319.246 g·mol−1 |
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It was patented in 1948 and came into medical use in 1955.[3] In 2021, the combination with dextromethorphan and pseudoephedrine was the 294th most commonly prescribed medication in the United States with more than 500,000 prescriptions.[4][5]