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Bio-FET
Type of field-effect transistor / From Wikipedia, the free encyclopedia
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A field-effect transistor-based biosensor, also known as a biosensor field-effect transistor (Bio-FET[1] or BioFET), field-effect biosensor (FEB),[2] or biosensor MOSFET,[3] is a field-effect transistor (based on the MOSFET structure)[3] that is gated by changes in the surface potential induced by the binding of molecules. When charged molecules, such as biomolecules, bind to the FET gate, which is usually a dielectric material, they can change the charge distribution of the underlying semiconductor material resulting in a change in conductance of the FET channel.[4][5] A Bio-FET consists of two main compartments: one is the biological recognition element and the other is the field-effect transistor.[1][6] The BioFET structure is largely based on the ion-sensitive field-effect transistor (ISFET), a type of metal–oxide–semiconductor field-effect transistor (MOSFET) where the metal gate is replaced by an ion-sensitive membrane, electrolyte solution, and reference electrode.[7]
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