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beta-Melanocyte-stimulating hormone
Chemical compound / From Wikipedia, the free encyclopedia
β-Melanocyte-stimulating hormone (β-MSH) is an endogenous peptide hormone and neuropeptide.[1] It is a melanocortin, specifically, one of the three types of melanocyte-stimulating hormone (MSH), and is produced from proopiomelanocortin (POMC).[1] It is an agonist of the MC1, MC3, MC4, and MC5 receptors.[1]
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Names | |
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Other names
beta-MSH, β-melanotropin, β-melanocortin, β-intermedin | |
Identifiers | |
3D model (JSmol) |
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PubChem CID |
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CompTox Dashboard (EPA) |
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Properties | |
C118H174N34O35S | |
Molar mass | 2660.95 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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β-MSH is artificially generated because it does not exist in humans naturally.[contradictory][2]
β-MSH is also known to decrease food intake in animals such as rats, chicken due to the effect of proopiomelanocortin (POMC).[3] Research was performed to see the effect β-MSH has on chicks, and it has been found that chicks responded with a decrease in food and water intake when treated with β-MSH. The experiment showed that β-MSH causes anorexigenic effects in chicks.[4]