Bamberger rearrangement
From Wikipedia, the free encyclopedia
The Bamberger rearrangement is the chemical reaction of phenylhydroxylamines with strong aqueous acid, which will rearrange to give 4-aminophenols.[1] It is named for the German chemist Eugen Bamberger (1857–1932).[2][3]
![The Bamberger rearrangement](http://upload.wikimedia.org/wikipedia/commons/thumb/1/19/Bamberger_rearrangement_scheme.svg/320px-Bamberger_rearrangement_scheme.svg.png)
The starting phenylhydroxylamines are typically synthesized by the transfer hydrogenation of nitrobenzenes using rhodium[4] or zinc[5] catalysts.
One application is in the synthesis of fenhexamid [fr].