Bacterial senescence
Gradual decrease in cellular function in individual bacteria / From Wikipedia, the free encyclopedia
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Bacterial senescence or bacterial aging refers to the gradual decrease in cellular function in individual bacteria as they increase in age. Indicators of senescence include a decelerated division rate and an increase likelihood of death.[1]
The fundamental cause of aging in bacteria is thought to be the accumulation of deleterious components (aging factors). Asymmetrically dividing bacteria, such as Caulobacter crescentus, show signs of replicative aging.[2] The results for symmetrically dividing bacteria are more nuanced. For example, Escherichia coli, under certain experimental conditions, may exhibit signs of replicative aging caused by subtle asymmetries in its division.[3][4][5]