Aspartame
Artificial non-saccharide sweetener / From Wikipedia, the free encyclopedia
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Aspartame is an artificial non-saccharide sweetener 200 times sweeter than sucrose and is commonly used as a sugar substitute in foods and beverages.[4] It is a methyl ester of the aspartic acid/phenylalanine dipeptide with brand names NutraSweet, Equal, and Canderel.[4] Aspartame was approved by the US Food and Drug Administration (FDA) in 1974, and then again in 1981, after approval was revoked in 1980.[4][5][6]
Names | |
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Pronunciation | /ˈæspərteɪm/ or /əˈspɑːrteɪm/ |
IUPAC name
Methyl L-α-aspartyl-L-phenylalaninate | |
Systematic IUPAC name
(3S)-3-amino-4-「[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino」-4-oxobutanoic acid | |
Other names
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Identifiers | |
3D model (JSmol) |
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2223850 | |
ChEBI | |
ChEMBL | |
ChemSpider |
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DrugBank |
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ECHA InfoCard | 100.041.132 |
EC Number |
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E number | E951 (glazing agents, ...) |
KEGG |
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PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C14H18N2O5 | |
Molar mass | 294.307 g·mol−1 |
Density | 1.347 g/cm3 |
Melting point | 246.5 °C (475.7 °F; 519.6 K)[2] |
Boiling point | Decomposes |
Sparingly soluble | |
Solubility | Slightly soluble in ethanol |
Acidity (pKa) | 4.5–6.0[3] |
Hazards[4] | |
NFPA 704 (fire diamond) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Aspartame is one of the most studied food additives in the human food supply.[7][8] Reviews by over 100 governmental regulatory bodies found the ingredient safe for consumption at the normal acceptable daily intake limit.[6][7][9][10][11][12][13]