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Medical condition From Wikipedia, the free encyclopedia
Arachnodactyly ("spider fingers") is a medical condition that is characterized by fingers and toes that are abnormally long and slender, in comparison to the palm of the hand and arch of the foot. In some cases, the thumbs of an individual with the condition are pulled inwards towards the palm. This condition is present at birth.
| Arachnodactyly | |
|---|---|
| Other names | Achromachia |
| |
| Bilateral arachnodactyly | |
| Specialty | Medical genetics  |
| Complications | None |
| Usual onset | Birth |
| Duration | Life-long |
| Causes | Mutations in the fibrillin-2 gene, in chromosome 5q23 |
This feature can occur on its own with no underlying health problems, or it can be associated with certain medical conditions, including Marfan syndrome,[1] Ehlers–Danlos syndromes,[2] Loeys–Dietz syndrome, and homocystinuria.[3] It is also seen in congenital contractural arachnodactyly,[4] which is caused by mutation in the gene encoding fibrillin-2 on chromosome 5q23.[5]
It remains unconfirmed whether composer Sergei Rachmaninoff's abnormally large reach on a piano was a result of arachnodactyly due to Marfan syndrome, as the pianist exhibited no other signs of the disease.[6]
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