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APC internal ribosome entry site (IRES)
RNA element / From Wikipedia, the free encyclopedia
The APC internal ribosome entry site (IRES) is an RNA element which is located in the coding sequence of the APC gene. APC is a tumour suppressor gene which is associated with the inherited disease adenomatous polyposis coli (APC). It is thought that IRES-mediated translation of APC is important for an apoptotic cascade.[1]
Quick Facts Identifiers, Symbol ...
APC internal ribosome entry site (IRES) | |
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![]() Predicted secondary structure and sequence conservation of IRES_APC | |
Identifiers | |
Symbol | IRES_APC |
Rfam | RF00462 |
Other data | |
RNA type | Cis-reg; IRES |
Domain(s) | Eukaryota |
GO | GO:0043022 |
SO | SO:0000243 |
PDB structures | PDBe |
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