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AM-906
Chemical compound / From Wikipedia, the free encyclopedia
AM-906 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid agonist. It is conformationally restricted by virtue of the double bond on its side chain, leading an increased affinity for and selectivity between CB1 and CB2 receptors.[1] It is a potent and selective agonist for the CB1 cannabinoid receptor, with a Ki of 0.8 nM at CB1 and 9.5 nM at CB2, a selectivity of almost 12x.[2]
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Formula | C23H34O3 |
Molar mass | 358.522 g·mol−1 |
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The corresponding E or trans isomer is AM-905.