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Chemical compound From Wikipedia, the free encyclopedia
4-Pyridylnicotinamide (4-PNA), also known as N-(pyridin-4-yl)nicotinamide, is a kinked dipodal dipyridine which was originally developed for use in chemotherapy.[1] As in its isomer 3-pyridylnicotinamide, the nitrogen atoms on its pyridine rings can donate their electron lone pairs to metal cations, allowing it to bridge metal centers and act as a bidentate ligand in coordination polymers.[2][3][4][5] It is synthesized through the reaction of nicotinoyl chloride and 4-aminopyridine.[1]
Names | |
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Preferred IUPAC name
N-(Pyridin-4-yl)pyridine-3-carboxamide | |
Other names
4-PNA; N-4-Pyridinyl-3-pyridinecarboxamide,; N-(Pyridin-4-yl)nicotinamide | |
Identifiers | |
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CompTox Dashboard (EPA) |
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Properties | |
C11H9N3O | |
Molar mass | 199.213 g·mol−1 |
Density | 1.287 g/cm3 |
Boiling point | 286.08 °C (546.94 °F; 559.23 K) |
Structure | |
0 D | |
Related compounds | |
Related compounds |
4,4'-bipyridine Pyridine Nicotinamide 4-Aminopyridine 3-Pyridylnicotinamide |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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