3-Monoacetylmorphine
Chemical compound / From Wikipedia, the free encyclopedia
3-Monoacetylmorphine (3-MAM) or 3-acetylmorphine is a less active metabolite of heroin (diacetylmorphine), the other two being morphine and more active 6-monoacetylmorphine (6-MAM).
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Other names | 3-Acetylmorphine, O(3)-monoacetylmorphine |
Routes of administration | Intravenous |
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ECHA InfoCard | 100.208.392 |
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Formula | C19H21NO4 |
Molar mass | 327.380 g·mol−1 |
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Because of the acetyl-group in 3-position, 3-MAM has relatively weak affinity to μ-opioid receptors.
As 3-O-acetylmorphine-6-O-sulfate (C19H23NO7S), where 6-OH is changed to 6-O-SO3, it can act as a potent, centrally acting morphine derivative and has important analgesic properties.[1][2][3]