POLD3

Protein sy'n cael ei godio yn y corff dynol gan y genyn POLD3 yw POLD3 a elwir hefyd yn DNA polymerase delta 3, accessory subunit (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q13.4.^[2]

POLD3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1U76, 3E0J, 2N1G
Dynodwyr
Cyfenwau	POLD3, P66, P68, PPP1R128, polymerase (DNA) delta 3, accessory subunit, DNA polymerase delta 3, accessory subunit
Dynodwyr allanol	OMIM: 611415 HomoloGene: 38202 GeneCards: POLD3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • DNA-directed DNA polymerase activity Cydrannau o'r gell • delta DNA polymerase complex • cnewyllyn cell • nucleoplasm • cytoplasm Prosesau biolegol • nucleotide-excision repair, DNA gap filling • DNA synthesis involved in DNA repair • DNA replication • translesion synthesis • transcription-coupled nucleotide-excision repair • nucleotide-excision repair, DNA incision • telomere maintenance • DNA-dependent DNA replication • nucleotide-excision repair, DNA incision, 5'-to lesion • GO:0100026 DNA repair • cellular response to DNA damage stimulus • telomere maintenance via semi-conservative replication • DNA mismatch repair • DNA strand elongation involved in DNA replication • DNA synthesis involved in UV-damage excision repair Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10714	n/a
Ensembl	ENSG00000077514	n/a
UniProt	Q15054	n/a
RefSeq (mRNA)	NM_006591 NM_001363597	n/a
RefSeq (protein)	NP_006582 NP_001350526	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn POLD3.

• P66
• P68
• PPP1R128

Llyfryddiaeth

• "Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage. ". Cell Cycle. 2012. PMID 22801543.
• "Phosphorylation of the C subunit (p66) of human DNA polymerase delta. ". Biochem Biophys Res Commun. 2008. PMID 18157942.
• "In vivo evidence for translesion synthesis by the replicative DNA polymerase δ. ". Nucleic Acids Res. 2016. PMID 27185888.
• "Multiple Forms of Human DNA Polymerase Delta Sub-Assembling in Cellular DNA Transactions. ". Curr Protein Pept Sci. 2016. PMID 26916162.
• "Break-induced replication repair of damaged forks induces genomic duplications in human cells.". Science. 2014. PMID 24310611.

Cyfeiriadau

1. "Human PubMed Reference:".
2. POLD3 - Cronfa NCBI