VAMP1

Protein sy'n cael ei godio yn y corff dynol gan y genyn VAMP1 yw VAMP1 a elwir hefyd yn Vesicle associated membrane protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12p13.31.^[2]

VAMP1
Dynodwyr
Cyfenwau	VAMP1, SPAX1, SYB1, VAMP-1, vesicle associated membrane protein 1, CMS25
Dynodwyr allanol	OMIM: 185880 HomoloGene: 40678 GeneCards: VAMP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • SNAP receptor activity • GO:0001948, GO:0016582 protein binding • syntaxin binding Cydrannau o'r gell • synaptic vesicle membrane • synapse • integral component of membrane • mitocondria • tertiary granule membrane • azurophil granule membrane • cell junction • integral component of plasma membrane • neuron projection • bilen • cell surface • specific granule membrane • mitochondrial outer membrane • cytoplasmic vesicle membrane • GO:0016023 cytoplasmic vesicle • cytosol • SNARE complex • integral component of synaptic vesicle membrane • neuromuscular junction • presynapse • glutamatergic synapse Prosesau biolegol • SNARE complex assembly • vesicle fusion • vesicle-mediated transport • exocytosis • synaptic vesicle priming • regulation of synaptic vesicle fusion to presynaptic active zone membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6843	n/a
Ensembl	ENSG00000139190	n/a
UniProt	P23763	n/a
RefSeq (mRNA)	NM_001297438 NM_014231 NM_016830 NM_199245	n/a
RefSeq (protein)	NP_001284367 NP_055046 NP_058439 NP_954740	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn VAMP1.

• SYB1
• SPAX1
• VAMP-1

Llyfryddiaeth

• "VAMP-1 has a highly variable C-terminus generated by alternative splicing. ". Biochem Biophys Res Commun. 1999. PMID 10544008.
• "Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility. ". Mol Neurodegener. 2015. PMID 25881291.
• "Homozygous mutations in VAMP1 cause a presynaptic congenital myasthenic syndrome. ". Ann Neurol. 2017. PMID 28253535.
• "Characterization of SNARE proteins in human pituitary adenomas: targeted secretion inhibitors as a new strategy for the treatment of acromegaly?". J Clin Endocrinol Metab. 2013. PMID 24152687.
• "Specificity of botulinum protease for human VAMP family proteins.". Microbiol Immunol. 2012. PMID 22289120.

Cyfeiriadau

1. "Human PubMed Reference:".
2. VAMP1 - Cronfa NCBI