GRK6

Protein sy'n cael ei godio yn y corff dynol gan y genyn GRK6 yw GRK6 a elwir hefyd yn Protein-serine/threonine kinase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q35.3.^[2]

GRK6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2ACX, 3NYN, 3NYO
Dynodwyr
Cyfenwau	GRK6, GPRK6, G protein-coupled receptor kinase 6
Dynodwyr allanol	OMIM: 600869 HomoloGene: 37570 GeneCards: GRK6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein kinase activity • protein serine/threonine kinase activity • GO:0001948, GO:0016582 protein binding • ATP binding • G protein-coupled receptor kinase activity • kinase activity • beta-adrenergic receptor kinase activity Cydrannau o'r gell • bilen • Cellbilen Prosesau biolegol • protein phosphorylation • Wnt signaling pathway • phosphorylation • regulation of G protein-coupled receptor signaling pathway • GO:0072468 signal transduction • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2870	n/a
Ensembl	ENSG00000198055	n/a
UniProt	P43250	n/a
RefSeq (mRNA)	NM_001004105 NM_001004106 NM_002082 NM_001364164	n/a
RefSeq (protein)	NP_001004105 NP_001004106 NP_002073 NP_001351093	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GRK6.

• GPRK6

Llyfryddiaeth

• "Prognostic value of decreased GRK6 expression in lung adenocarcinoma. ". J Cancer Res Clin Oncol. 2016. PMID 27601164.
• "Aberrant GRK6 promoter methylation is associated with poor prognosis in hypopharyngeal squamous cell carcinoma. ". Oncol Rep. 2016. PMID 26718636.
• "Association study of common variants within the G protein-coupled receptor kinase 6 gene and schizophrenia susceptibility in Han Chinese. ". Hum Psychopharmacol. 2014. PMID 24302161.
• "GRK6 expression in patients with hepatocellular carcinoma. ". Asian Pac J Trop Med. 2013. PMID 23375037.
• "The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs.". J Biol Chem. 2006. PMID 16613860.

Cyfeiriadau

1. "Human PubMed Reference:".
2. GRK6 - Cronfa NCBI