F5

Protein sy'n cael ei godio yn y corff dynol gan y genyn F5 yw F5 a elwir hefyd yn Coagulation factor V (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q24.2.^[2]

F5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3S9C, 1CZS, 1CZV, 3P6Z, 3P70
Dynodwyr
Cyfenwau	F5, FVL, PCCF, RPRGL1, THPH2, coagulation factor V
Dynodwyr allanol	OMIM: 612309 HomoloGene: 104 GeneCards: F5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • GO:0001948, GO:0016582 protein binding • copper ion binding Cydrannau o'r gell • platelet alpha granule • extracellular vesicle • endoplasmic reticulum lumen • bilen • Cellbilen • extracellular region • COPII-coated ER to Golgi transport vesicle • endoplasmic reticulum-Golgi intermediate compartment membrane • platelet alpha granule lumen • Golgi apparatus • Reticwlwm endoplasmig • Golgi membrane • extracellular space Prosesau biolegol • hemostasis • platelet degranulation • blood coagulation • blood circulation • endoplasmic reticulum to Golgi vesicle-mediated transport • COPII vesicle coating • response to vitamin K • post-translational protein modification Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2153	n/a
Ensembl	ENSG00000198734	n/a
UniProt	P12259	n/a
RefSeq (mRNA)	NM_000130	n/a
RefSeq (protein)	NP_000121	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn F5.

• FVL
• PCCF
• THPH2
• RPRGL1

Llyfryddiaeth

• "Targeting activated protein C to treat hemophilia. ". Curr Opin Hematol. 2017. PMID 28632502.
• "Factor V has an anticoagulant cofactor activity that targets the early phase of coagulation. ". J Biol Chem. 2017. PMID 28420729.
• "Joint effects of cancer and variants in the factor 5 gene on the risk of venous thromboembolism. ". Haematologica. 2016. PMID 27479824.
• "Association Between Thrombophilic Gene Mutations and the Risk of Vascular Access Thrombosis in Hemodialysis Patients. ". Ther Apher Dial. 2016. PMID 27004938.
• "Do incident and recurrent venous thromboembolism risks truly differ between heterozygous and homozygous Factor V Leiden carriers? A retrospective cohort study.". Eur J Intern Med. 2016. PMID 26970916.

Cyfeiriadau

1. "Human PubMed Reference:".
2. F5 - Cronfa NCBI