UTY

Histonska demetilaza UTY je enzim koji je kod ljudi kodiran genom UTY.^[3][4][5]

UTY
Dostupne strukture PDB Pretraga Human UniProta: PDBe RCSB Spisak PDB ID kodova 3ZLI, 3ZPO, 4UF0, 5FY0, 5FXW, 5FXX, 5FXZ, 5FY1, 5FY7, 5FYM, 5FXV, 5A1L
Identifikatori
Aliasi	UTY
Vanjski ID-jevi	OMIM: 400009 GeneCards: UTY
Lokacija gena (čovjek) Hrom. Hromosom Y[1] Bend Yq11.221 Početak 13,234,577 bp[1] Kraj 13,480,673 bp[1]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • oxidoreductase activity • dioxygenase activity • histone H3-tri/di-methyl-lysine-27 demethylase activity • vezivanje iona metala • histone demethylase activity • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • chromatin binding • chromatin DNA binding • sequence-specific DNA binding Ćelijska komponenta • jedro • nukleoplazma • MLL3/4 complex Biološki proces • Regulacija ekspresije gena • histone H3-K27 demethylation • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	7404	n/a
Ensembl	ENSG00000183878	n/a
UniProt	O14607	n/a
RefSeq (mRNK)	NM_001258249 NM_001258250 NM_001258251 NM_001258252 NM_001258253 NM_001258254 NM_001258255 NM_001258256 NM_001258257 NM_001258258 NM_001258259 NM_001258260 NM_001258261 NM_001258262 NM_001258263 NM_001258264 NM_001258265 NM_001258266 NM_001258267 NM_001258268 NM_001258269 NM_001258270 NM_007125 NM_182659 NM_182660 NM_001400170 NM_001400171 NM_001400173 NM_001400175 NM_001400177 NM_001400178 NM_001400181 NM_001400183 NM_001400185 NM_001400187 NM_001400189 NM_001400192 NM_001400195 NM_001400199	n/a
RefSeq (bjelančevina)	NP_001245178 NP_001245179 NP_001245180 NP_001245181 NP_001245182 NP_001245183 NP_001245184 NP_001245185 NP_001245186 NP_001245187 NP_001245188 NP_001245189 NP_001245190 NP_001245191 NP_001245192 NP_001245193 NP_001245194 NP_001245195 NP_001245196 NP_001245197 NP_001245198 NP_001245199 NP_009056 NP_872600 NP_872601 NP_001245196.1 NP_001245192.1 NP_001245178.1 NP_001245194.1 NP_001245186.1 NP_001245191.1 NP_001245187.1	n/a
Lokacija (UCSC)	Chr Y: 13.23 – 13.48 Mb	n/a
PubMed pretraga	[2]	n/a
Wikipodaci
Pogledaj/uredi – čovjek

Ovaj gen kodira protein koji sadrži tetratrikopeptid-ponavljanje za koji se smatra da je uključen u interakcije protein-protein. Manji je antigen histokompatibilnost, koji može inducirati odbacivanje transplantata presađenih muških matičnih ćelija. Alternativna prerada RNK rezultira u više varijanti transkripta koji kodiraju različite izoforme.^[5]

Interakcije

Pokazano je da UTY ima interakcije sa TLE1 ^[6] i WDR90.^[7]