USP51

Ubikvitinska karboksil-terminalna hidrolaza 51 je enzim koji je kod ljudi kodiran genom USP51.^[5][6]

USP51
Identifikatori
Aliasi	USP51
Vanjski ID-jevi	MGI: 3588217 HomoloGene: 71495 GeneCards: USP51
Lokacija gena (čovjek) Hrom. Hromosom X[1] Bend Xp11.21 Početak 55,484,616 bp[1] Kraj 55,489,848 bp[1]
Lokacija gena (miš) Hrom. Hromosom X (miš)[2] Bend X|X F3 Početak 151,789,465 bp[2] Kraj 151,792,412 bp[2]
Ontologija gena Molekularna funkcija • thiol-dependent deubiquitinase • vezivanje iona cinka • GO:0070122 peptidase activity • cysteine-type peptidase activity • hydrolase activity • vezivanje iona metala • chromatin binding • GO:0031493 histone binding Ćelijska komponenta • hromosom Biološki proces • protein deubiquitination • ubiquitin-dependent protein catabolic process • Proteoliza • histone deubiquitination • regulation of response to DNA damage stimulus • regulation of cell cycle process • regulation of double-strand break repair via homologous recombination • regulation of double-strand break repair via nonhomologous end joining • GO:0100026 Popravka DNK • cellular response to DNA damage stimulus Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	158880	635253
Ensembl	ENSG00000247746	ENSMUSG00000067215
UniProt	Q70EK9	B1AY15
RefSeq (mRNK)	NM_201286	NM_001137547
RefSeq (bjelančevina)	NP_958443	NP_001131019
Lokacija (UCSC)	Chr X: 55.48 – 55.49 Mb	Chr X: 151.79 – 151.79 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Reference

1. GRCh38: Ensembl release 89: ENSG00000247746 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000067215 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346.
6. "Entrez Gene: USP51 ubiquitin specific peptidase 51".

Dopunska literatura

• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Puente XS, López-Otín C (2004). "A genomic analysis of rat proteases and protease inhibitors". Genome Res. 14 (4): 609–22. doi:10.1101/gr.1946304. PMC 383305. PMID 15060002.
• Xie H, Diber A, Pollock S, et al. (2004). "Bridging expressed sequence alignments through targeted cDNA sequencing". Genomics. 83 (4): 572–6. doi:10.1016/j.ygeno.2003.07.003. PMID 15028280.
• Quesada V, Díaz-Perales A, Gutiérrez-Fernández A, et al. (2004). "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases". Biochem. Biophys. Res. Commun. 314 (1): 54–62. doi:10.1016/j.bbrc.2003.12.050. PMID 14715245.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.