Tamsulosin
Medication / From Wikipedia, the free encyclopedia
Tamsulosin, sold under the brand name Flomax among others, is a medication used to treat symptomatic benign prostatic hyperplasia (BPH) and chronic prostatitis and to help with the passage of kidney stones.[6][7][8] The evidence for benefit with a kidney stone is better when the stone is larger.[8] Tamsulosin is taken by mouth.[6]
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Pronunciation | /tæmˈsuːləsɪn/[1] tam-SOO-lə-sin |
Trade names | Flomax, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a698012 |
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Routes of administration | By mouth |
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Bioavailability | 100% (by mouth) |
Metabolism | Liver |
Elimination half-life | 9–13 hours |
Excretion | 76% Kidney |
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ECHA InfoCard | 100.109.780 |
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Formula | C20H28N2O5S |
Molar mass | 408.51 g·mol−1 |
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Common side effects include dizziness, headache, sleeplessness, nausea, blurry vision, and sexual problems.[9][6] Other side effects may include feeling lightheaded with standing due to changes in blood pressure, and angioedema.[9] Tamsulosin is an alpha blocker and works by relaxing muscles in the prostate.[10] Specifically it is an α1 adrenergic receptor blocker.[6]
Tamsulosin was approved for medical use in the United States in 1997.[6] It is available as a generic medication.[9] In 2021, it was the 24th most commonly prescribed medication in the United States, with more than 23 million prescriptions.[11][12]