Sinus tubercle
Proliferation of endoderm induced by the paramesonephric ducts / From Wikipedia, the free encyclopedia
Sinus tubercle (also known as sinual tubercle[1] or Müllerian eminence) is the proliferation of endoderm induced by the paramesonephric ducts. It is located in the developing fetus between the orifices of the mesonephric ducts on the urogenital sinus.[1] The uterovaginal primoridium, which is a fusion of the caudal ends of paramesonephric ducts, contacts the dorsal wall of the urogenital sinus and, induces the formation of the sinus tubercle. This occurs in both sexes:
- In the female, the mesonephric duct loses all association with the gonad and disappears. The sinus tubercle then gives rise to the sino-vaginal bulbs and, when it later becomes solid it is referred to as the vaginal plate.[1] It likewise gives rise to the hymen, which eventually breaks down in most cases.
- In the males, the sinus tubercle gives rise to the seminal colliculus.