![cover image](https://wikiwandv2-19431.kxcdn.com/_next/image?url=https://upload.wikimedia.org/wikipedia/commons/thumb/1/17/Protein_PAK2_PDB_1e0a.png/640px-Protein_PAK2_PDB_1e0a.png&w=640&q=50)
PAK2
Mammalian protein found in Homo sapiens / From Wikipedia, the free encyclopedia
Serine/threonine-protein kinase PAK 2 is an enzyme that in humans is encoded by the PAK2 gene.[5][6]
Quick Facts Available structures, PDB ...
Close
PAK2 is one of three members of Group I PAK family of serine/threonine kinases.[7][8] The PAKs are evolutionary conserved.[9] PAK2 and its cleaved fragment localize in both the cytoplasmic or nuclear compartments. PAK2 signaling modulates apoptosis,[10] endothelial lumen formation,[11] viral pathogenesis,[12] and cancer including, breast,[13] hepatocarcinoma,[14] and gastric [15] and cancer, at-large.[16]