39S ribosomal protein L39, mitochondrial is a protein that in humans is encoded by the MRPL39 gene.[5][6]
Quick Facts MRPL39, Available structures ...
MRPL39 |
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Identifiers |
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Aliases | MRPL39, C21orf92, L39mt, MRP-L5, MRPL5, PRED22, PRED66, RPML5, MSTP003, mitochondrial ribosomal protein L39, L5mt |
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External IDs | OMIM: 611845; MGI: 1351620; HomoloGene: 9679; GeneCards: MRPL39; OMA:MRPL39 - orthologs |
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Wikidata |
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.[6]