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LYN
Mammalian protein found in Homo sapiens / From Wikipedia, the free encyclopedia
Tyrosine-protein kinase Lyn is a protein that in humans is encoded by the LYN gene.[5]
For other uses, see Lyn (disambiguation).
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Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells,[6] in neural tissues[7] liver, and adipose tissue.[8] In various hematopoietic cells, Lyn has emerged as a key enzyme involved in the regulation of cell activation. In these cells, a small amount of LYN is associated with cell surface receptor proteins, including the B cell antigen receptor (BCR),[9][10] CD40,[11] or CD19.[12] The abbreviation Lyn is derived from Lck/Yes novel tyrosine kinase, Lck and Yes also being members of the Src kinase family.