Glycosylphosphatidylinositol
Phosphoglyceride attached to proteins / From Wikipedia, the free encyclopedia
Glycosylphosphatidylinositol (pronunciationā) or glycophosphatidylinositol (GPI) is a phosphoglyceride that can be attached to the C-terminus of a protein during posttranslational modification. The resulting GPI-anchored proteins play key roles in a wide variety of biological processes.[1] GPI is composed of a phosphatidylinositol group linked through a carbohydrate-containing linker (glucosamine and mannose glycosidically bound to the inositol residue) and via an ethanolamine phosphate (EtNP) bridge to the C-terminal amino acid of a mature protein. The two fatty acids within the hydrophobic phosphatidyl-inositol group anchor the protein to the cell membrane.
Quick Facts GPI synthesis components, Identifiers ...
GPI synthesis components | |
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Identifiers | |
Symbol | GPI |
Membranome | 327 |
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