File:Proton_pump_inhibitors_structure.svg
From Wikipedia, the free encyclopedia
Size of this PNG preview of this SVG file: 512 × 227 pixels. Other resolutions: 320 × 142 pixels | 640 × 284 pixels | 1,024 × 454 pixels | 1,280 × 568 pixels | 2,560 × 1,135 pixels.
Original file (SVG file, nominally 512 × 227 pixels, file size: 10 KB)
This is a file from the Wikimedia Commons. Information from its description page there is shown below. Commons is a freely licensed media file repository. You can help. |
Summary
DescriptionProton pump inhibitors structure.svg |
English: Common structure of proton pump inhibitors. Asterisk indicates stereocenter. Dots indicate lone pair. |
||||
Date | |||||
Source | Own work | ||||
Author | Anypodetos | ||||
Permission (Reusing this file) |
|
Compound | Substituents | Form | Cysteine binding | pKa | First approval | |||||
---|---|---|---|---|---|---|---|---|---|---|
X | R1 | R2 | R3 | R4 | pKaa1 | pKaa1 | year | |||
Omeprazole | CH | OCH3 | CH3 | CH3 | CH3 | Racemic mixture | 813 and 892 | 4.06 | 0.79 | 1989 in USA |
Esomeprazole | CH | OCH3 | CH3 | CH3 | CH3 | (S)-(−)-enantiomer of lansoprazole | 813 and 892 | 4.06 | 0.79 | 2001 in USA |
Lansoprazole | CH | H | CH3 | CH2CF3 | H | Racemic mixture | 813 and 321 | 3.83 | 0.62 | 1991 in Europe |
Dexlansoprazole | CH | H | CH3 | CH2CF3 | H | (R)-(+)-enantiomer of lansoprazole | 813 and 321 | 3.83 | 0.62 | 2009 in USA |
Pantoprazole | CH | OCHF2 | OCH3 | CH3 | H | Racemic mixture | 813 and 822 | 3.83 | 0.11 | 1994 in Germany |
Rabeprazole | CH | H | CH3 | (CH2)3OCH3 | H | Racemic mixture | 813, 892 and 321 | 4.53 | 0.62 | 1999 in USA |
Tenatoprazole | N | OCH3 | CH3 | CH3 | CH3 | Racemic mixture | 813 and 822 | 4.04 | –0.12 | — |
Licensing
I, the copyright holder of this work, hereby publish it under the following license:
This file is made available under the Creative Commons CC0 1.0 Universal Public Domain Dedication. | |
The person who associated a work with this deed has dedicated the work to the public domain by waiving all of their rights to the work worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law. You can copy, modify, distribute and perform the work, even for commercial purposes, all without asking permission.
http://creativecommons.org/publicdomain/zero/1.0/deed.enCC0Creative Commons Zero, Public Domain Dedicationfalsefalse |
Items portrayed in this file
depicts
7 February 2012
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 12:11, 7 December 2015 | 512 × 227 (10 KB) | Vaccinationist | facelifting | |
19:05, 8 February 2012 | 275 × 135 (35 KB) | Anypodetos | Mark stereocenter | ||
14:31, 7 February 2012 | 275 × 135 (34 KB) | Anypodetos | {{Information |Description ={{en|1=Common structure of {{w|proton pump inhibitor}}s}} |Source ={{own}} |Author =Anypodetos |Date =2012-02-07 |Permission = |other_versions = }} {{BKchem}}{{Inkscape}} [[C |
File usage
The following pages on the English Wikipedia use this file (pages on other projects are not listed):
Global file usage
The following other wikis use this file:
- Usage on ar.wikipedia.org
- Usage on bn.wikipedia.org
- Usage on fa.wikipedia.org
- Usage on fi.wikipedia.org
- Usage on fr.wikipedia.org
- Usage on ja.wikipedia.org
- Usage on ko.wikipedia.org
- Usage on la.wikipedia.org
- Usage on mk.wikipedia.org
- Usage on ms.wikipedia.org
- Usage on or.wikipedia.org
- Usage on ro.wikipedia.org
- Usage on sh.wikipedia.org
- Usage on sr.wikipedia.org
- Usage on th.wikipedia.org
- Usage on tr.wikipedia.org
- Usage on vi.wikipedia.org
- Usage on zh-yue.wikipedia.org
- Usage on zh.wikipedia.org
Metadata
This file contains additional information, probably added from the digital camera or scanner used to create or digitize it.
If the file has been modified from its original state, some details may not fully reflect the modified file.
Width | 100% |
---|---|
Height | 100% |