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Dynorphin A
Chemical compound / From Wikipedia, the free encyclopedia
Dynorphin A is a dynorphin, an endogenous opioid peptide that activates the κ-opioid receptor.[2] Its amino acid sequence is Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys.
Quick Facts Names, Identifiers ...
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Names | |
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Other names
Dynorphin 1-13 | |
Identifiers | |
PubChem CID |
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UNII | |
Properties | |
C75H126N24O15 | |
Molar mass | 1603.95474 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Dynorphin A1–8 is a truncated form of dynorphin A with the amino acid sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile.[3][4] Dynorphin A1–8 is an agonist at the mu-, kappa-, and delta-opioid receptors;[4] it has the highest binding affinity for the kappa-opioid receptor.[4] Structures of dynorphin A bound to the κ-opioid receptor have been reported.[2][5]