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Drosha
Ribonuclease III enzyme / From Wikipedia, the free encyclopedia
Drosha is a Class 2 ribonuclease III enzyme[5] that in humans is encoded by the DROSHA (formerly RNASEN) gene.[6][7][8] It is the primary nuclease that executes the initiation step of miRNA processing in the nucleus. It works closely with DGCR8 and in correlation with Dicer. It has been found significant in clinical knowledge for cancer prognosis[9] and HIV-1 replication.[10]
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