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Dihydroartemisinin
Drug used to treat malaria / From Wikipedia, the free encyclopedia
Dihydroartemisinin (also known as dihydroqinghaosu, artenimol or DHA) is a drug used to treat malaria. Dihydroartemisinin is the active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself. It is a semi-synthetic derivative of artemisinin and is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs.[1] It is sold commercially in combination with piperaquine and has been shown to be equivalent to artemether/lumefantrine.[2]
Quick Facts Clinical data, AHFS/Drugs.com ...
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Clinical data | |
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AHFS/Drugs.com | International Drug Names |
Routes of administration | By mouth |
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Pharmacokinetic data | |
Bioavailability | 12% |
Metabolism | Liver |
Elimination half-life | About 4–11 hours |
Excretion | Mainly bile |
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ECHA InfoCard | 100.128.242 ![]() |
Chemical and physical data | |
Formula | C15H24O5 |
Molar mass | 284.352 g·mol−1 |
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