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Cardiac glycoside
Class of organic compounds / From Wikipedia, the free encyclopedia
Cardiac glycosides are a class of organic compounds that increase the output force of the heart and decrease its rate of contractions by inhibiting the cellular sodium-potassium ATPase pump.[1] Their beneficial medical uses include treatments for congestive heart failure and cardiac arrhythmias; however, their relative toxicity prevents them from being widely used.[2] Most commonly found as secondary metabolites in several plants such as foxglove plants and milkweed plants, these compounds nevertheless have a diverse range of biochemical effects regarding cardiac cell function and have also been suggested for use in cancer treatment.[3]
Quick Facts Class identifiers, Use ...
Cardiac glycoside | |
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Drug class | |
![]() The general structure of a cardiac glycoside molecule. | |
Class identifiers | |
Use | Congestive heart failure |
ATC code | C01A |
Biological target | Na+ /K+ -ATPase |
External links | |
MeSH | D002301 |
Legal status | |
In Wikidata |
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