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Angiofibroma
Class of benign skin and mucous membrane lesions / From Wikipedia, the free encyclopedia
Angiofibroma (AGF) is a descriptive term for a wide range of benign skin or mucous membrane (i.e. the outer membrane lining body cavities such as the mouth and nose) lesions in which individuals have:
- benign papules, i.e. pinhead-sized elevations that lack visible evidence of containing fluid;
- nodules, i.e. small firm lumps usually >0.1 cm in diameter; and/or
- tumors, i.e. masses often regarded as ~0.8 cm or larger.
Quick Facts Specialty, Symptoms ...
Angiofibroma | |
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Angiofibroma, Hematoxylin and eosin stain, magnification ×10. | |
Specialty | Oncology ![]() |
Symptoms | Itchiness and sometimes bleeding.[1] |
Complications | Facial disfigurement and stigmatization.[1] |
Causes | Local overgrowth of collagen, fibroblasts, and blood vessels.[1] |
Risk factors | Tuberous sclerosis, Birt-Hogg-Dubé syndrome, and Multiple endocrine neoplasia type 1.[1] |
Diagnostic method | Skin biopsy.[1] |
Differential diagnosis | Intradermal melanocytic naevus, Acne, Basal cell carcinoma, Viral warts, Subungual exostosis, Molluscum contagiosum, and Anogenital warts.[1] |
Treatment | Excision, Dermabrasion, Using lasers, electrical, and radiofrequency devices, Cryotherapy, Topical podophyllotoxin, Topical rapamycin, and Topical beta-blockers.[1] |
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