ATOX1 is a copper metallochaperone protein that is encoded by the ATOX1 gene in humans.[5][6] In mammals, ATOX1 plays a key role in copper homeostasis as it delivers copper from the cytosol to transporters ATP7A and ATP7B.[7][8][9] Homologous proteins are found in a wide variety of eukaryotes, including Saccharomyces cerevisiae as ATX1, and all contain a conserved metal binding domain.[7][10]
Quick Facts Available structures, PDB ...
ATOX1 |
---|
![](//upload.wikimedia.org/wikipedia/commons/thumb/d/db/Protein_ATOX1_PDB_1fe0.png/250px-Protein_ATOX1_PDB_1fe0.png) |
Available structures |
---|
PDB | Ortholog search: PDBe RCSB |
---|
List of PDB id codes |
---|
1FE0, 1FE4, 1FEE, 1TL4, 1TL5, 2K1R, 2LQ9, 3CJK, 3IWL, 3IWX, 4QOT, 4YDX, 4YEA |
|
|
Identifiers |
---|
Aliases | ATOX1, ATX1, HAH1, antioxidant 1 copper chaperone |
---|
External IDs | OMIM: 602270; MGI: 1333855; HomoloGene: 2984; GeneCards: ATOX1; OMA:ATOX1 - orthologs |
---|
|
|
|
|
|
Wikidata |
|
Close