Tobramycin
Chemical compound / From Wikipedia, the free encyclopedia
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Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas.[8]
Quick Facts Clinical data, Trade names ...
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Trade names | Nebcin, Tobrex, Tobi, others |
Other names | 47663, SPRC-AB01 |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682660 |
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Routes of administration | Intravenous, intramuscular, inhalation, ophthalmic |
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Protein binding | Not bound[7] |
Metabolism | Not metabolized |
Elimination half-life | 2–3 hrs |
Excretion | Exclusively via kidneys |
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ECHA InfoCard | 100.046.642 |
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Formula | C18H37N5O9 |
Molar mass | 467.520 g·mol−1 |
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It was patented in 1965, and approved for medical use in 1974.[9] It is on the World Health Organization's List of Essential Medicines.[10] In 2021, it was the 299th most commonly prescribed medication in the United States, with more than 500,000 prescriptions.[11][12]