The sulfate transporter is a solute carrier family protein that in humans is encoded by the SLC26A2 gene.[5] SLC26A2 is also called the diastrophic dysplasia sulfate transporter (DTDST), and was first described by Hästbacka et al. in 1994.[5] A defect in sulfate activation described by Superti-Furga in achondrogenesis type 1B[6] was subsequently also found to be caused by genetic variants in the sulfate transporter gene.[7] This sulfate (SO42−) transporter also accepts chloride, hydroxyl ions (OH−), and oxalate as substrates.[8][9] SLC26A2 is expressed at high levels in developing and mature cartilage, as well as being expressed in lung, placenta, colon, kidney, pancreas and testis.[10][11]
Quick Facts SLC26A2, Identifiers ...
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