Sparfloxacin
Chemical to treat bacterial infections / From Wikipedia, the free encyclopedia
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Sparfloxacin is a fluoroquinolone antibiotic used in the treatment of bacterial infections. It has a controversial safety profile.[1]
Quick Facts Clinical data, Pronunciation ...
Clinical data | |
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Pronunciation | spar FLOX a sin |
Trade names | Spacin, Zagam, others |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
MedlinePlus | a600002 |
Routes of administration | By mouth |
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Pharmacokinetic data | |
Bioavailability | 92% |
Protein binding | 45% |
Metabolism | Hepatic glucuronidation Cytochrome P450 system not involved |
Elimination half-life | 16 to 30 hours |
Excretion | Fecal (50%) and renal (50%) |
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ECHA InfoCard | 100.157.238 |
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Formula | C19H22F2N4O3 |
Molar mass | 392.407 g·mol−1 |
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Melting point | 266 to 269 °C (511 to 516 °F) (dec.) |
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It was patented in 1985 and approved for medical use in 1993.[2] Zagam is no longer available in the United States.