Saccharomyces boulardii
Species of fungus / From Wikipedia, the free encyclopedia
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Saccharomyces boulardii is a tropical yeast first isolated from lychee and mangosteen fruit peel in 1923 by French scientist Henri Boulard. Although early reports claimed distinct taxonomic, metabolic, and genetic properties,[1] S. boulardii is genetically a grouping of S. cerevisiae strains, sharing >99% genomic relatedness, giving the synonym S. cerevisiae var. boulardii.[2][3][4]
Saccharomyces boulardii | |
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Scientific classification | |
Domain: | Eukaryota |
Kingdom: | Fungi |
Division: | Ascomycota |
Class: | Saccharomycetes |
Order: | Saccharomycetales |
Family: | Saccharomycetaceae |
Genus: | Saccharomyces |
Species: | S. boulardii |
Binomial name | |
Saccharomyces boulardii Seguela, Bastide & Massot, 1923 (nom. inval.) | |
Type strain | |
Hansen CBS 5926 | |
Synonyms | |
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S. boulardii is sometimes used as a probiotic with the purpose of introducing beneficial microbes into the large and small intestines and conferring protection against pathogens.[5][6][7] It grows at 37 °C (98.6 °F).[8] In addition, the popular genome-editing tool CRISPR-Cas9 was proven to be effective in S. boulardii.[9] Boulard first isolated this yeast after he observed natives of Southeast Asia chewing on the skin of lychee and mangosteen in an attempt to control the symptoms of cholera. In healthy patients, S. boulardii has been shown to be nonpathogenic and nonsystemic (it remains in the gastrointestinal tract rather than spreading elsewhere in the body).