Mannan-binding lectin serine protease 1 also known as mannose-associated serine protease 1 (MASP-1) is an enzyme that in humans is encoded by the MASP1 gene.[5][6][7]
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MASP1 |
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Identifiers |
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Aliases | MASP1, 3MC1, CRARF, CRARF1, MAP1, MASP, MASP3, MAp44, PRSS5, RaRF, mannan binding lectin serine peptidase 1, Mannan-binding lectin serine protease 1, MBL associated serine protease 1, MASP-3, MAP-1 |
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External IDs | OMIM: 600521; MGI: 88492; HomoloGene: 89143; GeneCards: MASP1; OMA:MASP1 - orthologs |
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Wikidata |
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MASP-1 is involved in the lectin pathway of the complement system and is responsible for activating MASP-2 and MASP-3.[8] It is also involved in the process of cleaving complement proteins, C4 and C2, into fragments to form a C3-convertase.[9]