Haplogroup DE
Human Y chromosome DNA grouping indicating common ancestry / From Wikipedia, the free encyclopedia
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Haplogroup DE is a human Y-chromosome DNA haplogroup. It is defined by the single nucleotide polymorphism (SNP) mutations, or UEPs, M1(YAP), M145(P205), M203, P144, P153, P165, P167, P183.[7] DE is unique because it is distributed in several geographically distinct clusters. An immediate subclade, haplogroup D (also known as D-CTS3946), is mainly found in East Asia, parts of Central Asia, and the Andaman Islands, but also sporadically in West Africa and West Asia. The other immediate subclade, haplogroup E, is common in Africa, and to a lesser extent the Middle East and southern Europe.
Haplogroup DE | |
---|---|
Possible time of origin | 68,500 years BP,[1] 68,555 years BP,[2] 70,000 years BP,[3] 76,500 years BP[4] |
Coalescence age | 65,200-76,500 years BP[1][4] |
Possible place of origin | Africa[5][4] or Eurasia[6] |
Ancestor | CT |
Descendants | E, D |
Defining mutations | M1/YAP, M145 = P205, M203, P144, P153, P165, P167, P183 |
The most well-known unique event polymorphism (UEP) that defines DE is the Y-chromosome Alu Polymorphism "YAP". The mutation was caused when a strand of DNA, known as Alu, inserted a copy of itself into the Y chromosome. Hence, all Y chromosomes belonging to DE, D, E and their subclades are YAP-positive (YAP+). All Y chromosomes that belong to other haplogroups and subclades are YAP-negative (YAP-).
The age of haplogroup DE, previously estimated at between 65,000 and 71,000 years,[8] was later estimated at around 68,555 years [2] and most recently at around 76,500 years old.[4]