Gramicidin S
Chemical compound / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Gramicidin S?
Summarize this article for a 10 year old
Gramicidin S or Gramicidin Soviet[1] is an antibiotic that is effective against some gram-positive and gram-negative bacteria as well as some fungi.
Clinical data | |
---|---|
Routes of administration | Topical |
Identifiers | |
| |
CAS Number |
|
PubChem CID | |
ChemSpider |
|
UNII | |
ChEBI | |
ChEMBL | |
NIAID ChemDB | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C60H92N12O10 |
Molar mass | 1141.470 g·mol−1 |
3D model (JSmol) | |
| |
| |
(verify) |
It is a derivative of gramicidin, produced by the gram-positive bacterium Brevibacillus brevis. Gramicidin S is a cyclodecapeptide, constructed as two identical pentapeptides joined head to tail, formally written as cyclo(-Val-Orn-Leu-D-Phe-Pro-)2. That is to say, it forms a ring structure composed of five different amino acids, each one used twice within the structure.[2] Another interesting point is that it utilizes two amino acids uncommon in peptides: ornithine as well as the atypical stereoisomer of phenylalanine. It is synthesized by gramicidin S synthetase.[3]