Edaravone
Chemical compound / From Wikipedia, the free encyclopedia
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Edaravone, sold under the brand name Radicava among others, is a medication used to treat stroke and amyotrophic lateral sclerosis (ALS).[4][5] It is given by intravenous infusion[4] and by mouth.[4][6]
Quick Facts Clinical data, Trade names ...
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Trade names | Radicava, others |
Other names | MCI-186 |
AHFS/Drugs.com | Monograph |
MedlinePlus | a617027 |
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Routes of administration | Intravenous, by mouth |
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ECHA InfoCard | 100.001.719 |
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Formula | C10H10N2O |
Molar mass | 174.203 g·mol−1 |
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The most common side effects include bruising (contusions), problems walking (gait disturbances), and headaches.[6]
The mechanism by which edaravone might be effective is unknown.[4] The medication is known to be an antioxidant, and oxidative stress has been hypothesized to be part of the process that kills neurons in people with ALS and in stroke victims.[7]
The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication.[8]