Ecallantide
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Ecallantide (trade name Kalbitor) is a drug used for the treatment of hereditary angioedema (HAE) and in the prevention of blood loss in cardiothoracic surgery.[2] It is an inhibitor of the protein kallikrein and a 60-amino acid polypeptide which was developed from a Kunitz domain through phage display to mimic antibodies inhibiting kallikrein.[2]
Quick Facts Clinical data, Trade names ...
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Trade names | Kalbitor |
Other names | DX-88 |
AHFS/Drugs.com | Monograph |
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Routes of administration | Subcutaneous injection |
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Elimination half-life | 1.5–2.5 hours |
Excretion | Kidney |
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Formula | C305H442N88O91S8 |
Molar mass | 7053.90 g·mol−1 |
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