ACADL
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Acyl-CoA dehydrogenase, long chain is a protein that in humans is encoded by the ACADL gene.[5]
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ACADL is a gene that encodes LCAD - acyl-CoA dehydrogenase, long chain - which is a member of the acyl-CoA dehydrogenase family. The acyl-CoA dehydrogenase family is primarily responsible for beta-oxidation of fatty acids within the mitochondria. LCAD dysfunction is associated with lowered fatty acid oxidation capacity and decreased heat generation. As a result, LCAD deficiency has been correlated with increased cardiac hypertrophy, pulmonary disease, and overall insulin resistance.[5]