Alzin jest protein koji je kod ljudi kodiran genom ALS2 sa hromosoma 2.[5][6] Ortolozi ALS2 [7] identificirani su kod svih sisara za koje su dostupni potpuni podaci o genomu.
Kratke činjenice Identifikatori, Aliasi ...
ALS2 |
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Identifikatori |
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Aliasi | ALS2 |
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Vanjski ID-jevi | OMIM: 606352 MGI: 1921268 HomoloGene: 23264 GeneCards: ALS2 |
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Ontologija gena |
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Molekularna funkcija | • protein homodimerization activity • guanyl-nucleotide exchange factor activity • protein serine/threonine kinase activator activity • GO:0001948, GO:0016582 vezivanje za proteine
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Ćelijska komponenta | • citoplazma • Vezikula • centrosom • membrana • GO:0097483, GO:0097481 postsynaptic density • intracellular membrane-bounded organelle • growth cone • ruffle • dendritična kičma • Akson • neuronal cell body • dendrit • early endosome • neuron projection • lamellipodium • citosol • GO:0009327 makromolekulani kompleks
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Biološki proces | • GO:0034613 protein localization • neuron projection morphogenesis • synaptic transmission, glutamatergic • axonogenesis • locomotory behavior • vesicle organization • GO:0043087, GO:0032313, GO:0032319, GO:0032314, GO:0043088 regulation of GTPase activity • Ćelijska smrt • in utero embryonic development • behavioral fear response • GO:0001306 response to oxidative stress • endosome organization • endosomal transport • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • receptor recycling • neuromuscular junction development • Rac protein signal transduction • regulation of Rho protein signal transduction • regulation of endosome size • positive regulation of Rac protein signal transduction • positive regulation of protein kinase activity • positive regulation of protein serine/threonine kinase activity
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Izvori:Amigo / QuickGO |
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Ortolozi |
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Vrste | Čovjek | Miš |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNK) | | |
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RefSeq (bjelančevina) | | |
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Lokacija (UCSC) | Chr 2: 201.7 – 201.78 Mb | Chr 1: 59.2 – 59.28 Mb |
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PubMed pretraga | [3] | [4] |
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Wikipodaci |
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Zatvori