Histone methylation

between histone methylation and malignant transformation of cells or formation of tumors. In recent years, epigenetic modification of the histone proteins

組蛋白甲基化（Histone methylation）是真核生物染色體上包裹DNA的組蛋白之離胺酸或精胺酸被甲基化的轉譯後修飾，多發生在組蛋白H3（英语：Histone H3）與組蛋白H4（英语：Histone H4）向外延伸的N端尾，此反應由组蛋白甲基转移酶（HMT）催化，將S-腺苷甲硫氨酸（SA

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails. Genes Dev. 2001, 15 (18):

(PDF)存档于2009-12-29）.  Grewal, S. I.; Rice, J. C. Regulation of heterochromatin by histone methylation and small RNAs. Current Opinion in Cell Biology. 2004, 16 (3): 230–238

; Dean, C. Vernalization requires epigenetic silencing of FLC by histone methylation. Nature. 2004, 427 (6970): 164–167. Bibcode:2004Natur.427..164B.