轉錄泡

轉錄泡泡（Transcription bubble）是在DNA轉錄過程中，當DNA雙鏈的局部解旋時所形成的分子結構。轉錄泡泡的大小範圍為12-14個鹼基對。當RNA聚合酶與啟動子結合並導致兩條DNA鏈分離時，就會形成轉錄泡泡。^[1]它顯示了一個未配對的DNA區域，在雙螺旋的每條鏈上都暴露出一小段核苷酸。^[1][2]

A molecular structure composed of unwound and unpaired DNA, where a short stretch of nucleotides are exposed on each strand of the double helix, allowing RNA polymerase binding, and nascent RNA synthesis within this region.

RNA聚合酶

參見

• 轉錄因子

參考資料

1. Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Morgan, David; Raff, Martin; Roberts, Keith; Walter, Peter. Wilson, John; Hunt, Tim , 编. Molecular Biology of the Cell 6. Garland Science. 2015: 306–307. ISBN 9781315735368. doi:10.1201/9781315735368 （英语）.
2. Clark, David P.; Pazdernik, Nanette J., Clark, David P.; Pazdernik, Nanette J. , 编, Chapter 2 - DNA, RNA, and Protein, Biotechnology (Second Edition) (Academic Cell), 2016-01-01: 33–61 [2019-09-30], ISBN 9780123850157, doi:10.1016/b978-0-12-385015-7.00002-8, （原始内容存档于2023-02-13）