趙安(1374年—1444年),陝西承宣布政使司臨洮府狄道縣(今甘肅省臨洮縣)人,明朝軍事將領、會川伯。

永樂元年,趙安進馬,除臨洮百戶,出使西域。后跟隨明成祖北伐有功,累進都指揮同知[1]宣德二年,松潘番叛,其擔任左參將,從總兵陳懷討平,進都督僉事。正統元年進都督同知,充右副總兵官,協任禮鎮甘肅。三年,與王驥任禮蔣貴分道進師,至刁力溝執右丞、達魯花赤等三十人。以功封會川伯,祿千石。明年移鎮涼州。正統九年十二月去世[2]

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