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来自维基百科,自由的百科全书
競爭性拮抗劑(英語:Competitive antagonist)是一種受體拮抗劑鍵結到受體後但並不活化受體。拮抗劑會跟促效劑競爭同受體上的結合位點。強效的拮抗劑會將促效劑從結合位點取代出來,使受體的活化減低。
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競爭性拮抗劑的存在將使促效作用的劑量-反應曲線向右橫移。[1]競爭性拮抗劑的Schild regression之斜率為1,且X、Y的截鉅跟拮抗劑的解離常數相等。[1]
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