Template:PBB/641維基百科,自由的 encyclopedia 事实速览 布盧姆綜合徵蛋白 BLM, 有效结构 ...布盧姆綜合徵蛋白BLM 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 2KV2, 2MH9, 2RRD, 3WE2, 3WE3, 4CDG, 4CGZ, 4O3M 标识代号 BLM; BS; RECQ2; RECQL2; RECQL3扩展标识 遗传学:604610 鼠基因:1328362 同源基因:47902 ChEMBL: 1293237 GeneCards: BLM GeneEC編號 3.6.4.12 基因本体论描述 分子功能 · bubble DNA binding · p53 binding · single-stranded DNA binding · ATP-dependent DNA helicase activity · helicase activity · protein binding · ATP binding · ATP-dependent helicase activity · four-way junction helicase activity · ATPase activity · annealing helicase activity · ATP-dependent 3'-5' DNA helicase activity · G-quadruplex DNA binding 细胞成分 · nuclear chromosome · chromosome, telomeric region · lateral element · male germ cell nucleus · nucleus · nucleoplasm · replication fork · nucleolus · cytoplasm · nuclear matrix · PML body · pronucleus 生物过程 · regulation of cyclin-dependent protein serine/threonine kinase activity · telomere maintenance · double-strand break repair via homologous recombination · DNA double-strand break processing · DNA strand renaturation · DNA repair · DNA recombination · cellular response to DNA damage stimulus · mitotic G2 DNA damage checkpoint · response to X-ray · protein sumoylation · replication fork processing · DNA duplex unwinding · post-translational protein modification · cellular protein metabolic process · positive regulation of transcription, DNA-templated · negative regulation of DNA recombination · negative regulation of mitotic recombination · alpha-beta T cell differentiation · positive regulation of alpha-beta T cell proliferation · replication fork protection · regulation of binding · protein oligomerization · negative regulation of cell division · negative regulation of thymocyte apoptotic process · cellular response to ionizing radiation · cellular response to hydroxyurea · cellular response to camptothecin Sources: Amigo / QuickGO 直系同源体物种 人类 小鼠Entrez 641 12144Ensembl ENSG00000197299 ENSMUSG00000030528UniProt P54132 O88700mRNA序列 NM_000057 NM_001042527蛋白序列 NP_000048 NP_001035992基因位置 Chr 15:90.72 – 90.82 Mb Chr 7:80.45 – 80.54 MbPubMed查询 [1] [2]查论编关闭
事实速览 布盧姆綜合徵蛋白 BLM, 有效结构 ...布盧姆綜合徵蛋白BLM 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 2KV2, 2MH9, 2RRD, 3WE2, 3WE3, 4CDG, 4CGZ, 4O3M 标识代号 BLM; BS; RECQ2; RECQL2; RECQL3扩展标识 遗传学:604610 鼠基因:1328362 同源基因:47902 ChEMBL: 1293237 GeneCards: BLM GeneEC編號 3.6.4.12 基因本体论描述 分子功能 · bubble DNA binding · p53 binding · single-stranded DNA binding · ATP-dependent DNA helicase activity · helicase activity · protein binding · ATP binding · ATP-dependent helicase activity · four-way junction helicase activity · ATPase activity · annealing helicase activity · ATP-dependent 3'-5' DNA helicase activity · G-quadruplex DNA binding 细胞成分 · nuclear chromosome · chromosome, telomeric region · lateral element · male germ cell nucleus · nucleus · nucleoplasm · replication fork · nucleolus · cytoplasm · nuclear matrix · PML body · pronucleus 生物过程 · regulation of cyclin-dependent protein serine/threonine kinase activity · telomere maintenance · double-strand break repair via homologous recombination · DNA double-strand break processing · DNA strand renaturation · DNA repair · DNA recombination · cellular response to DNA damage stimulus · mitotic G2 DNA damage checkpoint · response to X-ray · protein sumoylation · replication fork processing · DNA duplex unwinding · post-translational protein modification · cellular protein metabolic process · positive regulation of transcription, DNA-templated · negative regulation of DNA recombination · negative regulation of mitotic recombination · alpha-beta T cell differentiation · positive regulation of alpha-beta T cell proliferation · replication fork protection · regulation of binding · protein oligomerization · negative regulation of cell division · negative regulation of thymocyte apoptotic process · cellular response to ionizing radiation · cellular response to hydroxyurea · cellular response to camptothecin Sources: Amigo / QuickGO 直系同源体物种 人类 小鼠Entrez 641 12144Ensembl ENSG00000197299 ENSMUSG00000030528UniProt P54132 O88700mRNA序列 NM_000057 NM_001042527蛋白序列 NP_000048 NP_001035992基因位置 Chr 15:90.72 – 90.82 Mb Chr 7:80.45 – 80.54 MbPubMed查询 [1] [2]查论编关闭