Template:PBB/4297维基媒体模板 / 維基百科,自由的 encyclopedia 事实速览 髓样/淋巴样或混合世系白血病(三胸同源物,果蝇), 有效结构 ...髓样/淋巴样或混合世系白血病(三胸同源物,果蝇) PDB rendering based on 2j2s. 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 2AGH, 2J2S, 2JYI, 2KKF, 2KU7, 2KYU, 2LXS, 2LXT, 2W5Y, 2W5Z, 3EG6, 3EMH, 3LQH, 3LQI, 3LQJ, 3P4F, 3U85, 3U88, 4ESG, 4GQ6 标识代号 MLL; ALL-1; CXXC7; HRX; HTRX1; KMT2A; MLL/GAS7; MLL1A; TET1-MLL; TRX1; WDSTS扩展标识 遗传学:159555 鼠基因:96995 同源基因:4338 ChEMBL: 1293299 GeneCards: MLL GeneEC編號 2.1.1.43 基因本体论描述 分子功能 · AT DNA binding · sequence-specific DNA binding transcription factor activity · protein binding · zinc ion binding · histone methyltransferase activity (H3-K4 specific) · identical protein binding · protein homodimerization activity · transcription regulatory region DNA binding · unmethylated CpG binding · histone acetyl-lysine binding 细胞成分 · nucleus · histone methyltransferase complex · MLL1 complex 生物过程 · transcription from RNA polymerase II promoter · protein complex assembly · apoptotic process · positive regulation of transporter activity · embryonic hemopoiesis · histone H4-K16 acetylation · positive regulation of transcription, DNA-dependent · positive regulation of transcription from RNA polymerase II promoter · histone H3-K4 methylation · histone H3-K4 trimethylation · positive regulation of cellular response to drug Sources: Amigo / QuickGO RNA表达模式 更多表达数据直系同源体物种 人类 小鼠Entrez 4297 214162Ensembl ENSG00000118058 ENSMUSG00000002028UniProt Q03164 P55200mRNA序列 NM_001197104 NM_001081049蛋白序列 NP_001184033 NP_001074518基因位置 Chr 11:118.31 – 118.4 Mb Chr 9:44.8 – 44.88 MbPubMed查询 [1] [2]查论编关闭
事实速览 髓样/淋巴样或混合世系白血病(三胸同源物,果蝇), 有效结构 ...髓样/淋巴样或混合世系白血病(三胸同源物,果蝇) PDB rendering based on 2j2s. 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 2AGH, 2J2S, 2JYI, 2KKF, 2KU7, 2KYU, 2LXS, 2LXT, 2W5Y, 2W5Z, 3EG6, 3EMH, 3LQH, 3LQI, 3LQJ, 3P4F, 3U85, 3U88, 4ESG, 4GQ6 标识代号 MLL; ALL-1; CXXC7; HRX; HTRX1; KMT2A; MLL/GAS7; MLL1A; TET1-MLL; TRX1; WDSTS扩展标识 遗传学:159555 鼠基因:96995 同源基因:4338 ChEMBL: 1293299 GeneCards: MLL GeneEC編號 2.1.1.43 基因本体论描述 分子功能 · AT DNA binding · sequence-specific DNA binding transcription factor activity · protein binding · zinc ion binding · histone methyltransferase activity (H3-K4 specific) · identical protein binding · protein homodimerization activity · transcription regulatory region DNA binding · unmethylated CpG binding · histone acetyl-lysine binding 细胞成分 · nucleus · histone methyltransferase complex · MLL1 complex 生物过程 · transcription from RNA polymerase II promoter · protein complex assembly · apoptotic process · positive regulation of transporter activity · embryonic hemopoiesis · histone H4-K16 acetylation · positive regulation of transcription, DNA-dependent · positive regulation of transcription from RNA polymerase II promoter · histone H3-K4 methylation · histone H3-K4 trimethylation · positive regulation of cellular response to drug Sources: Amigo / QuickGO RNA表达模式 更多表达数据直系同源体物种 人类 小鼠Entrez 4297 214162Ensembl ENSG00000118058 ENSMUSG00000002028UniProt Q03164 P55200mRNA序列 NM_001197104 NM_001081049蛋白序列 NP_001184033 NP_001074518基因位置 Chr 11:118.31 – 118.4 Mb Chr 9:44.8 – 44.88 MbPubMed查询 [1] [2]查论编关闭