Template:PBB/641

布盧姆綜合徵蛋白 BLM
有效结构 PDB 直系同源检索：PDBe, RCSB PDB查询代码列表 2KV2, 2MH9, 2RRD, 3WE2, 3WE3, 4CDG, 4CGZ, 4O3M
标识
代号	BLM; BS; RECQ2; RECQL2; RECQL3
扩展标识	遗传学：604610 鼠基因：1328362 同源基因：47902 ChEMBL: 1293237 GeneCards: BLM Gene
EC編號	3.6.4.12
基因本体论描述 分子功能 · bubble DNA binding · p53 binding · single-stranded DNA binding · ATP-dependent DNA helicase activity · helicase activity · protein binding · ATP binding · ATP-dependent helicase activity · four-way junction helicase activity · ATPase activity · annealing helicase activity · ATP-dependent 3'-5' DNA helicase activity · G-quadruplex DNA binding 细胞成分 · nuclear chromosome · chromosome, telomeric region · lateral element · male germ cell nucleus · nucleus · nucleoplasm · replication fork · nucleolus · cytoplasm · nuclear matrix · PML body · pronucleus 生物过程 · regulation of cyclin-dependent protein serine/threonine kinase activity · telomere maintenance · double-strand break repair via homologous recombination · DNA double-strand break processing · DNA strand renaturation · DNA repair · DNA recombination · cellular response to DNA damage stimulus · mitotic G2 DNA damage checkpoint · response to X-ray · protein sumoylation · replication fork processing · DNA duplex unwinding · post-translational protein modification · cellular protein metabolic process · positive regulation of transcription, DNA-templated · negative regulation of DNA recombination · negative regulation of mitotic recombination · alpha-beta T cell differentiation · positive regulation of alpha-beta T cell proliferation · replication fork protection · regulation of binding · protein oligomerization · negative regulation of cell division · negative regulation of thymocyte apoptotic process · cellular response to ionizing radiation · cellular response to hydroxyurea · cellular response to camptothecin Sources: Amigo / QuickGO
直系同源体
物种	人类	小鼠
Entrez	641	12144
Ensembl	ENSG00000197299	ENSMUSG00000030528
UniProt	P54132	O88700
mRNA序列	NM_000057	NM_001042527
蛋白序列	NP_000048	NP_001035992
基因位置	Chr 15: 90.72 – 90.82 Mb	Chr 7: 80.45 – 80.54 Mb
PubMed查询	[1]	[2]
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